CNC Programmer / Operator Lead

At a Glance

Company:

Repligen

Location:

Shrewsbury, Massachusetts

Job Type:

Full-Time

Salary Range:

$85,000 – $100,000 per year (DOE)

Shift:

Day Shift (flexible depending on facility needs)

Overtime:

As needed during production ramp-up

Experience Level:

Senior / Lead

Industry:

Bioprocessing / Life Sciences Manufacturing

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Why This Role Exists

Repligen is launching a

new manufacturing facility in Shrewsbury, MA , and this role is critical to building a strong CNC programming foundation from the ground up.

As the

Lead CNC Programmer , you’ll help establish programming standards, support new equipment installs, and mentor a growing team—playing a direct role in scaling production for life-saving biologic therapies used worldwide.

This is not a “sit behind the desk” role. It’s hands-on, technical, and influential.

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The Work You’ll Be Doing

In this role, you will:

Develop, modify, and optimize

CNC programs for milling, turning, and multi-axis machines

Serve as the

technical lead

for CNC programming and machining strategy

Review and approve CNC programs, setups, and tooling selections

Lead program prove-outs, first articles, and production ramp-ups

Partner with Engineering on

DFM and new product introductions

Establish programming standards, documentation, and setup sheets

Mentor and train CNC programmers and machinists

Support safety, quality, and regulatory compliance

Drive continuous improvement and lean manufacturing initiatives

You’ll have real ownership over how CNC programming is done at this facility.

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Machines, Controls & Software

You’ll work directly with equipment such as:

Machines:

NexTech CNC Router

Laguna CNC Router

Controls:

CNC router controls (machine-specific)

CAM Software:

Mastercam, Fusion 360, SolidWorks CAM

Inspection:

First article and in-process inspection support

This role will also help shape programming standards as additional equipment is brought online.

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What We’re Looking For

Required

5+ years of CNC programming experience in a manufacturing environment

Advanced proficiency with

G-code and CAD/CAM software

Strong knowledge of machining processes, tooling, materials, and

GD&T

Experience supporting

new equipment installs or facility start-ups

Proven ability to mentor others and solve machining problems hands-on

Preferred (Not Required)

Experience in regulated manufacturing environments

Exposure to multi-axis machining strategies

Background supporting production ramp-ups or greenfield facilities

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Materials You’ll Work With

Stainless steels

Aluminum alloys

Engineering plastics

Other precision manufacturing materials

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Why Machinists & Programmers Like Working Here

Brand-new manufacturing facility

Opportunity to

build systems and standards , not inherit bad ones

High-impact work supporting life-saving biologic therapies

Cross-functional collaboration with engineering and quality

Strong emphasis on quality, safety, and craftsmanship

Real leadership path as the site scales

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Pay, Benefits & Schedule

Salary:

$85,000 – $100,000 DOE

Medical, dental, and vision insurance

401(k) with company match

Paid time off and holidays

Long-term career growth in a mission-driven manufacturing environment

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Apply

Interested CNC Programmers ready to step into a

technical leadership role

can apply directly through

hireCNC .

Apply now or save this job to come back later.