Scientist

At Ncardia, we believe iPSC technology is the key to improving the clinical success of new therapeutics. By combining deep iPSC expertise, broad assay capabilities, and a strong understanding of human disease biology, we empower drug developers to make critical decisions earlier and with greater confidence. Our expertise spans from iPSC generation, large-scale differentiation, and cell manufacturing to disease modeling, assay development, and screening. Whether you need high-quality cells, relevant screening assays, or robust iPSC differentiation processes, Ncardia is your trusted partner. Visit www.ncardia.com for more information.

The position

As a Scientist in iPSC manufacturing and drug discovery services, you will be responsible for developing and optimizing differentiation processes and analytical methods to advance iPSC-derived drug discovery. You will play a key role in executing and managing projects, contributing to scientific innovation, and working collaboratively across teams. Your expertise in iPSC culture and differentiation, molecular biology, and assay development will be essential to advancing our manufacturing and drug discovery programs. You are a highly motivated scientist with a problem-solving mindset and a strong ability to work in dynamic and collaborative environments. You thrive on innovation and scientific excellence and are capable of managing multiple projects while maintaining quality and efficiency. You are open-minded, a strong communicator, and a true team player who enjoys working in both research and service-oriented environments.

Responsibilities

Design and optimize differentiation strategies for iPSC-derived manufacturing Develop and validate analytical methods to characterize differentiated cell products Execute research projects, analyze data, and provide scientific interpretations Collaborate with cross-functional teams to ensure project success Stay updated on the latest scientific advancements in iPSC technology and drug discovery Contribute to scientific publications, presentations, and internal knowledge sharing Draft and review Standard Operating Procedures (SOPs) Assess effects of putative therapeutics (small molecules, antibodies, siRNA/shRNA, antisense oligonucleotides, AAV) and analyze obtained data independently Collect, record and report data accurately following standard operation procedures Communicate routinely with team members to facilitate discussion on progress as well as possible challenges and opportunities

Qualifications

Ph.D. or M.Sc. in molecular biology, cell biology, genetics, or a related field Hands-on experience with iPSC culture and differentiation techniques Strong background in stem cell and cell culture Experience with assay development and analytical method validation Excellent problem-solving and data analysis skills Experience in a Life Sciences/Biotech company or CRO Experience with complex in vitro biology, such as stem cells and 3D/organoid culturing is preferred Familiarity with the following techniques: aseptic in vitro cell culture, cell-based assays, tissue engineering and organoid formation, flow cytometry, high-content imaging, luminescence/fluorescence/absorbance assays, metabolic assays, electrophysiology, calcium-imaging, laboratory automation Strong organizational and time management abilities Effective communication and teamwork skills Proficiency in English (written and spoken)

Additional experience of value:

Experience in gene editing techniques Experience in the use of bioreactors Knowledge of bioprocessing and scalable differentiation strategies

Job Location:

Leiden, The Netherlands Position Type:

Full-Time. Weekend work required on schedule. Start Date:

Immediately

We offer you a challenging position in a dynamic biotech company with room for personal growth and development. We provide a competitive salary package based on your education and experience.

Interested?

Send your motivation letter with curriculum vitae to careers@ncardia.com