HEOR Modeler

Role: HEOR Modeler Education Master’s or PhD in

Health Economics, Public Health, Outcomes Research, Health Services Research, Pharmacy, Economics, Biostatistics, or a related discipline Experience 5–10 years

hands-on experience in HEOR modeling within: Pharmaceutical / Biotech companies HEOR consultancies CROs / Market Access agencies Technical Skills Strong expertise in

Excel-based economic modeling

(advanced formulas, macros preferred). Experience with

modeling and statistical tools , such as: R Python / VBA TreeAge WinBUGS / JAGS (for Bayesian analyses, desirable) Strong understanding of: HTA methods Economic evaluation principles Modeling best practices Domain Knowledge Proven experience in one or more

therapeutic areas

(e.g., Oncology, Rare Diseases, Immunology, Cardiovascular, Metabolic, Neurology). Strong understanding of

payer evidence expectations

across regions (US, EU, UK, APAC).

Key Responsibilities Health Economic Modeling Design, develop, and validate

health economic models , including: Cost-effectiveness models (CEA) Cost-utility models (CUA) Budget impact models (BIM) Cost-consequence models Develop

decision-tree, Markov, partitioned survival, and patient-level simulation (microsimulation)

models. Clearly document model structure, assumptions, data sources, and limitations in line with HTA expectations. Evidence Integration Integrate

clinical trial data, real-world evidence (RWE), network meta-analysis (NMA), indirect treatment comparisons (ITC) , and epidemiology data into models. Collaborate with epidemiology, biostatistics, and RWE teams to ensure fit-for-purpose evidence selection. Conduct

deterministic and probabilistic sensitivity analyses , scenario analyses, and value-of-information analyses. Market Access & HTA Support Support global and local

HTA submissions

(e.g., NICE, ICER, CADTH, G-BA, HAS, PBAC). Support

pricing and reimbursement strategy , value dossiers, and payer value stories. Respond to

HTA queries, critiques, and model validation requests . Cross-functional Collaboration Work closely with

Medical Affairs, Market Access, RWE, Biostatistics, Epidemiology, and Commercial teams . Provide strategic input into evidence generation plans and economic endpoints. Support client interactions, workshops, and payer-facing discussions (as applicable). Quality & Governance Ensure compliance with

ISPOR, CHEERS, NICE, and country-specific HTA guidelines . Perform internal quality checks, peer reviews, and model audits. Mentor junior HEOR analysts/modelers and contribute to capability building.