Head of Clinical Operations

Head of Clinical Operations – Remote, EU – Mid-sized specialist CRO - Rare Diseases

Upsilon Global is partnering with an innovative, mid-sized European CRO specialising in complex, multi-country clinical trials across rare and specialty therapeutic areas. With a strong scientific foundation and a reputation for quality over volume, this organisation delivers Phase I to III studies for biotech and pharmaceutical partners who need agility, expertise, and true operational partnership rather than a transactional service model.

Due to continued growth across Europe, they are now seeking a Head of Clinical Operations to lead, shape, and scale their clinical function. This is a strategic leadership role for someone who wants genuine ownership, influence at senior level, and the opportunity to build something meaningful rather than simply maintain it.

Background Details confidential, information available upon request.

Main responsibilities To oversee and lead European clinical operations Ensuring regulations, SOPs and GCP guidelines followed Managing budgets, deadlines, planning, resourcing and compliance Being the first point of contact for both internal and external meetings Maintaining the correct levels of resources Interviewing clinical personnel to expand the team when necessary Managing clinical and administrative personnel; this will include motivating, employing, training and assessing performances. Reporting KPIs to management and implementing solutions to meet targets Assessing company policy and modifying solutions when necessary Contributing to the development of clinical SOPs and department guidelines to meet regulatory, ethical and clinical standards Setting agreed project targets and overseeing the quality of deliverables from the Clinical Operations teams across Europe Supporting daily duties including: responding to inquiries from clinical sites, project members and client requests Representing the Clinical Operations Department for proposals, budgets, P&L topics and contracts for the European market

Education and Qualifications Lifesciences degree or similar, PhD/MSc preferable Minimum of 10 years’ industry experience across either CRO, pharmaceutical or biotech Extensive knowledge of European regulatory requirements, MHRA and EMEA, ICH/GCP guidelines Proven track record in the delivery of clinical programmes across Europe and globally Previous experience working with rare diseases preferable

Other skills and abilities In depth knowledge of, and skill in applying, applicable clinical research regulatory requirements, i.e., Good Clinical Practice (GCP) and International Conference on Harmonisation (ICH) guidelines Ability to lead the clinical team, acting as advocate for the group Strong communication and interpersonal skills, including good command of English language Good presentation skills Ability to establish and maintain effective working relationships with co-workers, staff and clients.

For more information please apply