Postdoctoral Researcher - H/F

Postdoctoral Researcher - H/F at

INSERM

Base pay range This range is provided by INSERM. Your actual pay will be based on your skills and experience — talk with your recruiter to learn more.

Overview of INSERM INSERM is the only French public organisation entirely dedicated to biological, medical and population health research. It has research laboratories throughout France, grouped into 12 Regional Delegations. Our institute brings together 15,000 researchers, engineers, technicians and administrative staff with a common goal: to improve everyone's health through advances in knowledge about living organisms and diseases, innovation in treatments and public health research.

Joining INSERM means joining an institute committed to gender parity and professional equality, diversity and support for its employees with disabilities, from recruitment and throughout their careers. In order to promote well‑being at work, INSERM pursues an active policy on working conditions, based in particular on a fair balance between personal and professional life.

In 2016, INSERM was awarded the European HR Excellence in Research label and is committed to developing its recruitment and evaluation practices for researchers.

Paris Cardiovascular Research Centre (PARCC) PARCC conducts cutting‑edge research encompassing clinical, translational and fundamental sciences in the cardiovascular field. Its strategic research areas are structured around three priorities: Gene and molecular signalling; Immunity and metabolism; Predictive models and multidimensional approaches.

For each strategic area, PARCC develops a continuum between fundamental research, innovative development, translational research and patient benefit. These strategic priorities are developed in four main pathological contexts, targeting multi‑organ diseases: macro‑ and microvascular pathologies associated with metabolic diseases, heart failure and sudden cardiac death, endocrine and resistant hypertension, renal hypertension pathologies and transplantation.

Main mission The successful candidate will work on an ANR‑funded project aimed at studying the role of macrophages in cardiac fibrosis using single‑cell and spatial transcriptomics methods.

Main activities

Animal models of cardiovascular diseases (surgery)

Management of transgenic mouse lines

Conducting and analysing single‑cell and spatial transcriptomics experiments

Presenting results at international conferences

Preparing figures for scientific publications

Writing scientific publications (in English)

Specific features and environment of the position Emerging Inserm CPJ team within the Paris Centre for Cardiovascular Research‑Inserm U970, team of approximately 5 to 8 people. International team, English is the working language for both spoken and written communication.

Knowledge

Cell biology

Molecular biology

Bioinformatics

Cardiac pathophysiology

Immunology, macrophage study models

Cardio‑immunology

Fluent spoken/written scientific English

Hard skills

Extensive experience in animal experimentation

Extensive experience in animal surgery for cardiovascular pathology models

Extensive experience in managing transgenic mouse lines

Experience in preparing samples and single‑cell RNA‑seq libraries

Extensive experience in single‑cell RNA‑seq analysis and spatial transcriptomics: analysis of multi‑omics single‑cell RNA‑seq data and spatial transcriptomics with R or Python bioinformatics

Packages, data integration, data mining, etc.

Extensive experience in flow cytometry

Soft skills

Scientific rigour and organisation

Autonomy

Ability to work in a team

Desired experience 2 to 4 years post‑doctorate

Level of qualification and training Bac +8

Seniority level Internship

Employment type Full‑time

Job function Research, Analyst, and Information Technology

Industries Research Services

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