Job offer

Organisation/Company Inserm- Institut Mondor Department COHEN Team Research Field Biological sciences » Biology Medical sciences » Cancer research Researcher Profile First Stage Researcher (R1) Positions Postdoc Positions Application Deadline 31 Mar 2026 - 20:00 (Europe/Paris) Country France Type of Contract Temporary Job Status Full-time Hours Per Week 38h30 Offer Starting Date 3 May 2026 Is the job funded through the EU Research Framework Programme? Not funded by a EU programme Is the Job related to staff position within a Research Infrastructure? No Offer Description

Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal cancers, characterized by a profoundly immunosuppressive tumor microenvironment (TME) and a poor response to current immunotherapies. The TME displays limited T‑cell infiltration and an abundance of regulatory and myeloid cells that dampen anti‑tumor immunity. Our team previously demonstrated that a combined immunotherapy strategy targeting TNFR2 on regulatory T cells, together with CD40 agonist stimulation , can effectively reinvigorate anti‑tumor immune responses in patients. Understanding how treatment shapes the immune landscape and defining predictive biomarkers

will be central to the project through high‑dimensional single‑cell and spatial technologies. This work has strong translational potential for optimizing

immunotherapy strategies for PDAC patients. Where to apply

E-mail ilaria.cascone@inserm.fr Requirements

Research Field Biological sciences » Biology Education Level PhD or equivalent Skills/Qualifications PhD in immunology, oncology, cancer biology, or a related field Strong expertise in immunological techniques (flow cytometry, in vitro assays, mouse models) Experience with tumor microenvironment studies or immunotherapy is an asset Interest or experience in single‑cell or spatial omics approaches Motivation to contribute to translational research bridging fundamental mechanisms and clinical application Ability to work collaboratively within multidisciplinary networks Languages ENGLISH Level Good Languages FRENCH Level Basic Research Field Biological sciences » BiologyMedical sciences » Cancer research Additional Information

Selection process CV Brief cover letter describing your research experience and interest

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