Senior Full Stack Engineer

We are currently looking for a Senior Full Stack Engineer to join our growing Web Applications team. reporting to the Engineering Manager, you’ll work on complex projects that span both front-end and back-end, with an initial focus on web infrastructure for our FastAPI and Next.js platform. In this role, you’ll optimize our build and deployment strategy for the front-end, including designing dynamic bundling approaches (e.g., per-customer builds, code splitting, tree-shaking) and improving performance across the stack through profiling, analysis, and optimization of both front-end rendering (Core Web Vitals, TTFT) and back-end async workflows. You’ll also contribute to the scalability of our FastAPI services, enhance our async programming practices, and support the evolution of SOA and microservice architectures. On the front-end, you’ll partner with product and design teams to integrate and extend our design systems and component libraries, ensuring accessible, reusable, and performant UI components. Finally, you’ll collaborate closely with the Security team to proactively identify and remediate vulnerabilities in dependencies, libraries, and web infrastructure.

Pay range Pay range:

$130,000 - 180,000

We know compensation is an important part of choosing your next role. The range shown reflects our target hiring range, informed by market data, internal equity, and the role’s current scope. Often the mid-range is where we tend to fall, but individual offers may vary based on experience, skills, and the role scope.

You Will

Implement new features and bug fixes as part of a larger cross-functional team of data engineers, product managers, designers, and scientists

Work within your immediate team of 4-6 full-stack engineers to do technical investigations, solution designs, code implementation with automated tests, and code reviews

Architect and implement sophisticated, stateful client-side workflows and user interfaces using modern state management patterns, ensuring a resilient and maintainable data layer.

Architect and implement sophisticated, stateful user interfaces, designing a resilient client-side data layer that seamlessly integrates with our FastAPI backend through well-defined API contracts and efficient state management patterns.

Drive the evolution of our overall web architecture, making critical decisions on how our Next.js frontend and FastAPI backend interact. This includes shaping our API strategy, defining data fetching patterns, and structuring our applications to ensure scalability and performance from the database to the browser.

Lead or consult the authoring of engineering design proposals following our product roadmap at BenchSci

Leverage a deep understanding of the business context and the team’s goals to unlock independent technical decisions in the face of open-ended requirements

Proactively identify new opportunities (from both internal and external sources) and advocates for and implements improvements to the current state of projects

Adhere to and improve our high standards of highly scalable and maintainable code

Help set a high standard for exceptional engineers who are outcome-oriented and improve the team's culture

Be given an unmatched opportunity for accelerated growth and learn from a team of world-class engineers

Provide troubleshooting analysis and resolution in a timely manner

Work on projects involving some of the largest pharmaceutical companies in the world

Solve difficult problems and bring new perspectives to the team

You Have

A degree in Computer Science/Engineering or a related field within science

High comfort working with a React/Typescript front-end and a Python back-end

4+ years of experience working as a professional full-stack developer

Deep expertise in modern state management solutions (e.g., React Query, SWR, Zustand, Redux Toolkit) and the ability to architect scalable data-fetching and caching strategies on the client.

Experience working with or contributing to design systems and component libraries (Storybook, Radix, Material UI, shadcn/ui, etc.), with a focus on reusability, accessibility, and performance.

Experience delivering and optimizing applications over global CDNs at scale.

Proven track record in performance analysis: able to profile, benchmark, and optimize both frontend rendering (React/ Next.js ) and backend request lifecycles (FastAPI, Python).

Deep understanding of web performance metrics (Core Web Vitals, TTFT, TTFB, Lighthouse) and how to optimize them.

Experience with dynamic imports, tree-shaking, and code splitting strategies in Next.js / Webpack.

Solid understanding of relational databases and SQL (PostgreSQL, MySQL or similar)

Experience working with cloud platforms (AWS, GCP, Azure)

Excellent communication and collaboration skills

Strong problem-solving and analytical skills

Experience with Frontend and Backend testing frameworks (Jest, Cypress, PyTest, etc.)

Strong familiarity with server-less architectures, including trade-offs around cold starts, cost optimization, and scalability.

Strong understanding of the Python and Typescript type systems

Deep expertise in modern bundling tools and strategies (Webpack, Vite, Turbopack, or similar).

Must have strong experience with asynchronous programming (Python asyncio, FastAPI async endpoints, event loops, non-blocking I/O).

Familiarity with caching strategies (edge caching, reverse proxies, Redis, etc.) to improve scalability and latency.

Nice To Have

Hands-on experience designing hybrid architectures that combine server-less, edge, and traditional compute models to optimize for latency and cost.

Ability to conduct load testing and stress testing (Locust, k6, JMeter) to validate scalability goals.

Experience building and deploying applications using edge functions (e.g., Vercel Edge, Cloudflare Workers, AWS Lambda@Edge).

Experience with multi-tenant SaaS architectures and customer-specific builds or deployments.

Experience working with Service-Oriented Architectures (SOA) and microservices at scale.

Experience with static site generation (SSG), incremental static regeneration (ISR), or hybrid Next.js rendering patterns.

Experience designing theming and customization strategies for multi-tenant SaaS products (supporting customer-specific branding at scale).

Familiarity with accessibility standards (WCAG, ARIA) and ensuring they are embedded in the design system.

Experience creating and consuming Model Context Protocol (MCP) servers, enabling integration with LLMs, tools, and services.

Experience with DevOps practices and tools

Ability and willingness to mentor other engineers

Benefits and Perks

A great compensation package that includes BenchSci equity options

A robust vacation policy plus an additional vacation day every year

Company closures for 14 more days throughout the year

Flex time for sick days, personal days, and religious holidays

Comprehensive health and dental benefits

Annual learning & development budget

A one-time home office set-up budget to use upon joining BenchSci

An annual lifestyle spending account allowance

Generous parental leave benefits with a top-up plan or paid time off options

The ability to save for your retirement coupled with a company match!

About BenchSci BenchSci's mission is to exponentially increase the speed and quality of life-saving research and development. We empower scientists to run more successful experiments with the world's most advanced, biomedical artificial intelligence software platform. Backed by Generation Investment Management, TCV, Inovia, F-Prime, Golden Ventures, and Google's AI fund, Gradient Ventures, we provide an indispensable tool for scientists that accelerates research at top pharmaceutical companies and leading academic centers.

Our Culture Our culture fosters transparency, collaboration, and continuous learning. We value each other's differences and always look for opportunities to embed equity into the fabric of our work. We foster diversity, autonomy, and personal growth, and provide resources to support motivated self-leaders in continuous improvement. You will work with high-impact, highly skilled, and intelligent experts motivated to drive impact and fulfill a meaningful mission. We empower you to unleash your full potential, do your best work, and thrive. Here you will be challenged to stretch yourself to achieve the seemingly impossible.

Diversity, Equity and Inclusion We're committed to creating an inclusive environment where people from all backgrounds can thrive. We believe that improving diversity, equity and inclusion is our collective responsibility, and this belief guides our DEI journey. Learn more about our DEI initiatives.

Accessibility Accommodations Should you require any accommodation, we will work with you to meet your needs. Please reach out to

[email protected] .

We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.

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