Job Description
Nurix Therapeutics is a clinical stage biopharmaceutical company focused on the discovery, development, and commercialization of targeted protein degradation medicines, the next frontier in innovative drug design aimed at improving treatment options for patients with cancer and inflammatory diseases. Powered by a fully AI-integrated discovery engine capable of tackling any protein class, and coupled with unparalleled ligase expertise, Nurix’s dedicated team has built a formidable advantage in translating the science of targeted protein degradation into clinical advancements. Nurix aims to establish degrader-based treatments at the forefront of patient care, writing medicine’s next chapter with a new script to outmatch disease.
This role owns the business systems that support Nurix’s path from clinical trials through commercialization. You will be the primary IT partner to Clinical Operations, Regulatory, Quality, and Commercial leadership, ensuring the technology they depend on works and evolves with the business.
The scope includes clinical systems (EDC, eTMF, pharmacovigilance, regulatory submissions), quality and training platforms, and commercial systems as they come online. You manage vendor relationships for delivery outcomes, work with Quality on validation requirements, and coordinate with IT Strategy & Vendor Operations on contracts and shared infrastructure.
This is a strategic role with hands‑on expectations. You will define requirements, design workflows, run implementations, and ensure adoption. If a vendor falls short or a gap emerges, you can configure, troubleshoot, or build what’s needed. You’re not above the work.
The goal is to function as a mini‑CIO for the life sciences enterprise application portfolio. Over time, the role grows with the company. As Nurix advances toward commercial stage, you will shape the systems strategy and build a team to support it.
Primary Responsibilities
Serve as primary IT partner to Clinical Operations, Regulatory, Quality, and Commercial
Translate business needs into system requirements and implementation plans
Own stakeholder satisfaction for the enterprise applications portfolio
Proactively identify technology opportunities that enable business outcomes
Own the clinical, quality, regulatory, and commercial application portfolio
ERP/back‑office systems as commercial operations expand
Define application roadmap aligned to clinical milestones and commercial readiness
Manage system integrations, data flows, and reporting needs
Implementation and delivery
Lead implementations end‑to‑end: requirements, configuration, testing, training, go‑live
Coordinate with clinical PM contractor on project execution
Align with IT Project Manager on resource conflicts, shared vendors, and portfolio reporting
Manage UAT coordination, training development, and change management
Own functional relationships with application vendors (what gets built, does it work, is it adopted)
Partner with Director, IT Strategy & Vendor Operations on contracts, SOWs, and vendor governance
Hold vendors accountable for delivery outcomes and service quality
Ensure vendors build internal capability, not dependency
Compliance and quality
Partner with Quality on GxP validation requirements for regulated systems
Understand CSV principles; work alongside Qualitas and internal validation resources
Support FDA inspection readiness for IT‑related controls
Ensure 21 CFR Part 11 compliance for electronic records and signatures Organization
Required Qualifications
10+ years in IT, with 5+ years in life sciences or pharmaceutical environments
Direct experience with clinical systems: EDC, eTMF, CTMS, safety/PV, or regulatory submissions
Veeva platform experience (Vault, CRM, QMS)
Medidata Rave experience
Track record leading application implementations from requirements through adoption
Experience managing vendors for delivery outcomes (not just contract administration)
Working knowledge of GxP validation principles and 21 CFR Part 11
Strong business analyst skills: requirements gathering, process design, stakeholder facilitation
Comfortable with hands‑on configuration and troubleshooting when needed
Effective communicator with scientific, clinical, and business audiences
Bachelor’s degree in a technical field, or equivalent experience
Strongly Preferred Qualifications
Experience supporting regulatory submissions or FDA inspection readiness
Commercial systems experience (CRM, market access, patient services)
ERP implementation or administration experience
Organization
Reports to:
SVP IT
Key partners:
Director, IT Operations (contracts, vendor governance, shared infrastructure)
Clinical PM contractor (implementation project execution)
Sr. Director and CISO (security, compliance)
USDM (system validation, GxP compliance)
Primary stakeholders:
Clinical Operations leadership
Regulatory Affairs leadership
Quality leadership
Commercial leadership
Salary Range:
$216,000 to $251,000 Plus Bonus and Equity
Location:
Brisbane, CA - Onsite
As set forth in Nurix’s Equal Employment Opportunity policy, we do not discriminate on the basis of any protected group status under any applicable law.
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